In vitro study of ethanolic, cold and hot-water extracts of Cymbopogon\ncitratus, Moringa oleifera, Ocimum gratissimum and Clerodendrum volubile was determined\nagainst toxigenic Aspergillus flavus. The antifungal efficacies of the medicinal\nplants were investigated using agar well diffusion technique and minimum inhibitory\nconcentration. The phytochemical constituents of the plants were also investigated. It\nwas observed that, hot-water extract of C. citratus was most effective against toxigenic\nA. flavus, cold water extract of M. oleifera was effective against toxigenic A. flavus, the\nmost antifungal effect of O. gratissimum and C. volubile were efficient using ethanolic\nextraction method. One thousand milligrams per millilitres concentration of these\nplant extracts had inhibitory effect on toxigenic A. flavus. The results of phytochemical\nscreening of the plant extracts for the detection of volatile oil, glycoside, tannins and\nsaponins shows that saponin and tannin, were detected in the ethanolic, cold and hotwater\nextract of M. oleifera, O. gratissimum and C. volubile. These result of the research\nindicates that ethanolic extracts of M. oleifera, O. gratissimum and C. volubile are used\nto cure infections caused by toxigenic A. flavus and the extracts may have role as pharmaceutical\nand preservatives.
Loading....